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On the Disney XD cartoon Milo Murphy's Law, there are three main characters, those being the eponymous Milo Murphy, and his two friends Melissa Chase and Zack Underwood. A majority of the episodes star and feature these three characters in their daily lives as a middle schooler, although it is possible for Melissa or Zack to either have a minor role in certain episodes, or to not appear at all.

List of Main Characters

Image Name Description
TS79 Milo Murphy Milo is the protagonist of Milo Murphy's Law, voiced by "Weird Al" Yankovic. He has a reputation for inheriting Murphy's Law and bringing bad luck with him, but he is always optimistic and finds ways to overcome it. He carries a seemingly bottomless backpack with him that always seems to have what he needs for any given situation. It was given to him by his old babysitter, Veronica, whom was the only one able to handle Murphy's Law.
Screenshot (3258) Melissa Chase Melissa, voiced by Sabrina Carpenter, is the show's deuteragonist and a long-time friend of Milo's who likes to hang out with him despite his bad luck, being the first person brave enough to hang out with him. She is quite smart, but also a little scatterbrained, as she often forgets some of her personal belongings. Melissa is also extremely confident and enjoys betting on the results of Murphy's Law.
Llama 11 Zack Underwood Voiced by Mekai Curtis, Zack is the show's tritagonist, and the new kid in Danville who becomes friends with Milo and Melissa, sticking by Milo's side, despite Murphy's Law. As the new kid, Zack often fills the role of a straight man. He was once the lead singer of a boy band called The Lumberzacks, and later leads a new band with Milo and Melissa. Zack also appears claustro-avoidant, and has a fear of fish.


  • The three main characters trust each other with anything, such as sharing their secret with each other ("Secrets and Pies"), as well as their fears ("Murphy's Lard").
  • Milo is the youngest of the three main characters, while Zack is the oldest.
  • Melissa is the only girl in the group of main characters. She's also the only main character whose eyes have pupils.


The image gallery for the Main Characters as a group may be viewed here.

See Also

v - e - d Characters
Milo MurphyMelissa ChaseZack Underwood
Balthazar CavendishVinnie DakotaDiogeeMartin MurphyBrigette MurphySara MurphyAmanda LopezMort SchaefferBradley NicholsonElliot DeckerOrton Mahlson
Families Murphy: Martin MurphyBrigette MurphySara MurphyMilo MurphyDiogeeJoey MurphyLaura MurphyNate MurphyGrandpa MurphyGrandma MurphySheriff MurphyMurphy Family
Underwood: Marcus UnderwoodEileen UnderwoodZack Underwood
Chase: Richard ChaseMelissa Chase
Jefferson County
Middle School
Students: Amanda LopezMort SchaefferBradley NicholsonChad Van CoffLydiaJoni
Staff: Elizabeth MilderKyle DrakoMs. MurawskiNolan MitchellMs. WhipleyFredMr. Hartoonian
Bureau of
Time Travel
Mr. BlockGretchenCavendishDakotaBrickSavannah
The Doctor
Zone Files
Show and Cast: Orton MahlsonDoctor ZoneTime Ape
Fans: KrisWallyJosh
Phineas and Ferb
Dr. DoofenshmirtzPerry the PlatypusMajor MonogramCarl KarlPhineas FlynnFerb FletcherCandace FlynnJeremy JohnsonBuford Van StommBaljeet TjinderIsabella Garcia-Shapiro
Antagonists Pistachions: King PistachionDerekDennisJerryBrandiPistachions (in general)
Other Antagonists: Sentient BlobVictor Verliezer
Kids and Teens: NealThe LumbermaxesMaxJackieBrulee twin sistersWendyLizzyLola SunderguardLola Sunderguard's Friends
Adults: Elliot DeckerScottVeronicaTobias TrollhammerClyde RickenbackerMr. BruleeMrs. BruleeMs. BaxterShelleyForemanDaveJavierSlashGretchen FlammkuchenPhillipGovernment AgentsJefferson G. CountyEuniceMayor
Misc: Lardee BoyC.I.D.D.AliensMinor Characters