In the series itself, Dr. Zone is a time-traveling alien cyborg who was one of the last survivors of a doomed planet. He was separated from his brother and mother by the escape ship that was used to send him off the planet as an infant, because it only had room for one of them. After becoming an adult and acquiring his Time Bee-icle, Dr. Zone encountered another time-traveler, a trans-chronological being who had a form beyond the comprehension of any normal person. So he changed his appearance to become Time Ape. Later, The Doctor Zone Files the Movie Files revealed that Time Ape is, in fact, Dr. Zone's brother. He had been mutated when their planet imploded but later re-assumed his true form when he re-entered his brother's reality.
In "Missing Milo," the premiere of the formerly lost black-and-white pilot episode — "The Seed Beasts" — shows him having a conversation with Milo.
He has brown hair, light skin, and is slender-built. He wears a black trench coat and a dark brown hat with square goggles on it. A maroon waistcoat is underneath it, along with a white shirt and an orange cravat. He has a gift box on his right arm. His left foot is robotic or he wears a metallic boot. On his right foot he wears a brown-strapped sandal belonging to the ancient Roman era. He also has a metallic backpack.